Clinical periodontal parameters and sub-gingival bacterial profile in chronic periodontitis patients with and without chronic kidney disease (CKD)

Objectives: To assess the severity of periodontitis and to determine the sub-gingival microbial profile in patients with and without chronic kidney disease (CKD). Methods: A total of 40 patients (18 females and 22 males) were selected for the study and were divided into two groups of twenty each. The test group (Group I) consisted of 20 patients (8 females and 12 males) chronic periodontitis with chronic kidney disease, and control group (Group II) had 20 patients(10 males and 10 females) chronic periodontitis without chronic kidney disease (CKD).Clinical periodontal parameters such as PPD(pocket probing depth),CAL(clinical attachment loss),BOP (bleeding on probing) and Sub-Gingival Bacterial profile. Results: Results of this study suggests that clinical parameters such as PPD (pocket probing depth), CAL(clinical attachment loss), BOP (bleeding on probing) and sub-gingival bacterial profile belonging to red complex are significantly more in patients with CKD. Conclusion: CP presented more severe clinical parameters and is associated with increased frequency of trponema denticolae, tanerella forsythia, porphyromonas gingivalis in patients with CKD.