2022•World Journal of PsychiatryOpen access

Difference between treatment-resistant schizophrenia and clozapine-resistant schizophrenia

Ping‐Tao Tseng, Mu‐Hong Chen, Chih‐Sung Liang

Abstract

We read the impressive review article "Clozapine resistant schizophrenia: Newer avenues of management" with great enthusiasm and appreciation. The author believes that preventing clozapine resistance from developing may be the most effective treatment strategy for patients with clozapine-resistant schizophrenia (CRS), and optimizing clozapine treatment is a key component. Disentangling the differences between treatment-resistant schizophrenia and CRS is important for studies addressing treatment strategies for these difficult-to-treat populations.

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Key concepts: Clozapine, Schizophrenia (object-oriented programming), Medicine, Psychiatry, Management of schizophrenia, Enthusiasm, Antipsychotic, Psychology