Nanostructured and molecular ROS generators for Photo- and Sonodynamic therapy
Antonina Dadadzhanova, Ekaterina Kolesova, В. Г. Маслов, Joseph Kost, Anna Orlova
Abstract
Antonina Dadadzhanova, Ekaterina Kolesova, В. Г. Маслов, Joseph Kost, Anna Orlova
Abstract
Sonodynamic therapy can dramatically enhance the efficiency of non-invasive tumor treatment due to multiple mechanisms initiating cell apoptosis or necrosis under ultrasound action combined with molecular and nanostructured sonosensitizers. Recently, we have demonstrated for the first time the sonodynamic effect of low-intensity 20 kHz ultrasound combined with chlorin e6 on melanoma cells.
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Sonodynamic therapy can dramatically enhance the efficiency of non-invasive tumor treatment due to multiple mechanisms initiating cell apoptosis or necrosis under ultrasound action combined with molecular and nanostructured sonosensitizers. Recently, we have demonstrated for the first time the sonodynamic effect of low-intensity 20 kHz ultrasound combined with chlorin e6 on melanoma cells.
Key concepts: Sonodynamic therapy, Photodynamic therapy, Ultrasound, Cancer research, Materials science, Medicine, Chemistry, Radiology