2021•Unpublished venueRequires access

Antiretroviral Resistance

Carolyn Chu, Lealah C Pollock, Robert W. Shafer

Abstract

Abstract This chapter outlines various mechanisms of HIV drug resistance as well as HIV drug resistance testing assays and clinical considerations. Transmitted HIV drug resistance and acquired HIV drug resistance are discussed in detail. Unique considerations regarding evaluation of HIV drug resistance and management for select clinical scenarios are reviewed. These scenarios include switches or simplification of the antiretroviral regimen, pregnancy, recent use of preexposure prophylaxis, “rapid” antiretroviral therapy, and care of persons with HIV in low- and middle-income countries.

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Available abstract

Key concepts: Antiretroviral drug, Human immunodeficiency virus (HIV), HIV drug resistance, Drug resistance, Antiretroviral therapy, Medicine, Regimen, ANTIRETROVIRAL AGENTS