Formulation, Development, and In-Vitro Evaluation of a Film-Coated Tablet Containing a Flavonoid Diosmin and Hesperidin Combination

In this study combination of diosmin and hesperidin was used for the treatment of a condition called chronic venous insufficiency. diosmin and hesperidin are citrus bioflavonoids that act as a vascular-protecting agents used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins. A preformulation study was carried out for the formulation of the tablet of the selected drug. A compatibility study was carried out between diosmin and hesperidin along with excipients like