ANALGESIC EFFICACY POST MAJOR ORTHOPAEDIC SURGERY – A COMPARATIVE STUDY: DICLOFENAC VS TRAMADOL
Ashwin Syam S
Abstract
Open-access reader
Ashwin Syam S
Abstract
Open-access reader
Post-operative pain management is a major concern in orthopaedic surgery. Every surgeon has a post-op pain management protocol, though the ideal regimen or combo was always a debate. NSAIDs and Opioids occupy the majority in pain management regimen. In this study, the analgesic efficacy of Tramadol hydrochloride (Opioid) and Diclofenac sodium (NSAID) in patients undergoing a major orthopedic surgery was investigated and compared. A total of 50 randomly selected preoperatively and were grouped into receiving either one of the drug. Postoperative pain was evaluated by using a visual analogue scale (VAS) assessing at 6,12,18,24,32,40,48,56,64,72,80,88,96,104,112,120 hours post-surgery. Tramadol hydrochloride showed significance in the early postoperative period(<40 hours) but later anti- inflammatory action of Diclofenac sodium indicates to be an enhanced analgesic (64 to 104 hours). However, no significance was noted in VAS score after 104 hours post-surgery.
OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Post-operative pain management is a major concern in orthopaedic surgery. Every surgeon has a post-op pain management protocol, though the ideal regimen or combo was always a debate. NSAIDs and Opioids occupy the majority in pain management regimen. In this study, the analgesic efficacy of Tramadol hydrochloride (Opioid) and Diclofenac sodium (NSAID) in patients undergoing a major orthopedic surgery was investigated and compared. A total of 50 randomly selected preoperatively and were grouped into receiving either one of the drug. Postoperative pain was evaluated by using a visual analogue scale (VAS) assessing at 6,12,18,24,32,40,48,56,64,72,80,88,96,104,112,120 hours post-surgery. Tramadol hydrochloride showed significance in the early postoperative period(<40 hours) but later anti- inflammatory action of Diclofenac sodium indicates to be an enhanced analgesic (64 to 104 hours). However, no significance was noted in VAS score after 104 hours post-surgery.
Key concepts: Medicine, Tramadol, Diclofenac, Analgesic, Tramadol Hydrochloride, Diclofenac Sodium, Visual analogue scale, Anesthesia