2022•European Journal of Drug Metabolism and PharmacokineticsRequires access

Evaluation of an Ussing Chamber System Equipped with Rat Intestinal Tissues to Predict Intestinal Absorption and Metabolism in Humans

Chi Guan, Yingxin Yang, Dong Bo Tian, Zhiqiang Jiang, Huiying Zhang, Yali Li, Jiaxiu Yan, Congman Zhang, Chun Chen, Junhua Zhang, Jing Wang, Yu Wang, Hongwen Du, Hongyu Zhou, Tao Wang

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Key concepts: Ussing chamber, Intestinal permeability, Bioavailability, Biopharmaceutics Classification System, First pass effect, Pharmacology, Efflux, Absorption (acoustics)