RESULT OF PLATELETPHERESIS AND ANTI-PLATELET MEDICATION IN TREATMENT OF ESSITIAL THROMBOCYTHEMIA AT VIETNAM - CZECH FRIENDSHIP HOSPITAL IN 2017 - 2019

The study was carried out in 56 essential thrombocytosis patients admitted to Vietnam - Czech hospital in Hai Phong city from 01/01/2017 to 06/2019. Subject: Investigation of the effectiveness of plateletpheresis and anti - platelet medication treatment (combined with hydroxyurea) in essential thrombocytosis. Method: prospective study with clinical intervention. Results: 1. The effectiveness of plateletpheresis. 1.1. Most of patients have improvement regarding symptoms related to microvascular stasis due to thrombocytosis (reduced from 58,3% to 31,8% with p < 0,05). 1.2. After 24 hours of plateletpheresis, platelet count reduced from 1,340 G/l to 736 G/l. 2. The effectiveness of anti-platelet medication after plateletpheresis: after 2 weeks of treatment, most of patients have significant improvements regarding symptoms related to microvascular stasis due to thrombocytosis (reduced from 31,8% to 3,8%).