2022•PLoS BiologyOpen access

Whole-proteome structures shed new light on posttranslational modifications

Robbie P. Joosten, Jon Agirre

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Abstract

Accurate but protein-only AlphaFold models may show structural fingerprints of likely posttranslational modifications (PTMs). In this issue of PLOS Biology, Bludau and colleagues add a functional context to models by combining them with readily available proteomics results.

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Accurate but protein-only AlphaFold models may show structural fingerprints of likely posttranslational modifications (PTMs). In this issue of PLOS Biology, Bludau and colleagues add a functional context to models by combining them with readily available proteomics results.

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Available abstract

Accurate but protein-only AlphaFold models may show structural fingerprints of likely posttranslational modifications (PTMs). In this issue of PLOS Biology, Bludau and colleagues add a functional context to models by combining them with readily available proteomics results.

Key concepts: Biology, Posttranslational modification, Proteome, Computational biology, Proteomics, Context (archaeology), Bioinformatics, Genetics

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