2022•International Journal of Advanced ResearchOpen access

DIRECT COMPRESSIBLE AND CO-PROCESSED EXCIPIENTS- A REVIEW

Dhaneshwar Kumar Vishwakarma Jai Narayan Mishra, Hema Gupta, Akella Anuradha

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Abstract

The demands on the functionality of excipients are increasing day by day because of the emergence of high-speed tableting machines and the use of direct compression methods for tableting. Direct compressible is the preferred method for the preparation of tablet. Excipient play an important role in formulating a dosage form. these are the ingredient which along with active pharmaceutical ingredient make up the dosage forms. Excipient act as protective agent, bulking agent and can also be used sources of excipients along with their uses, and these Can be used for different activities. The current review article highlights the information about Direct compressible and co-processing excipients and their advantages. Also, the recent developments in excipient technology with special emphasis on natural combinations that could be used as co-processed excipients are briefly discussed.

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The demands on the functionality of excipients are increasing day by day because of the emergence of high-speed tableting machines and the use of direct compression methods for tableting. Direct compressible is the preferred method for the preparation of tablet. Excipient play an important role in formulating a dosage form. these are the ingredient which along with active pharmaceutical ingredient make up the dosage forms. Excipient act as protective agent, bulking agent and can also be used sources of excipients along with their uses, and these Can be used for different activities. The current review article highlights the information about Direct compressible and co-processing excipients and their advantages. Also, the recent developments in excipient technology with special emphasis on natural combinations that could be used as co-processed excipients are briefly discussed.

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Available abstract

The demands on the functionality of excipients are increasing day by day because of the emergence of high-speed tableting machines and the use of direct compression methods for tableting. Direct compressible is the preferred method for the preparation of tablet. Excipient play an important role in formulating a dosage form. these are the ingredient which along with active pharmaceutical ingredient make up the dosage forms. Excipient act as protective agent, bulking agent and can also be used sources of excipients along with their uses, and these Can be used for different activities. The current review article highlights the information about Direct compressible and co-processing excipients and their advantages. Also, the recent developments in excipient technology with special emphasis on natural combinations that could be used as co-processed excipients are briefly discussed.

Key concepts: Tableting, Excipient, Active ingredient, Dosage form, Pharmaceutical technology, Ingredient, Biochemical engineering, Materials science

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