2022International Journal of Health SciencesOpen access

Primary hyperaldosteronism without suppressed renin

Sarath Bhaskar, V. Padma, R Murugaraj, B Abhilash Nair, Dr Kannan Meera Devi, Saketh Ramineni

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Abstract

Primary Hyperaldosteronism characterizes elevated plasma and urinary aldosterone with suppression of plasma renin activity. Suppression can be due to sodium retention which is aldosterone dependent and extracellular volume expansion. Here a 29 year old male presented with uncontrolled hypertension, on work up he was diagnosed to have primary Hyperaldosteronism with normal plasma renin level. So with the available medical data on the patient as well as the publications on aldosterone/renin association in primary hyperaldosteronism was reviewed here to explain the rare finding.

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Primary Hyperaldosteronism characterizes elevated plasma and urinary aldosterone with suppression of plasma renin activity. Suppression can be due to sodium retention which is aldosterone dependent and extracellular volume expansion. Here a 29 year old male presented with uncontrolled hypertension, on work up he was diagnosed to have primary Hyperaldosteronism with normal plasma renin level. So with the available medical data on the patient as well as the publications on aldosterone/renin association in primary hyperaldosteronism was reviewed here to explain the rare finding.

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Available abstract

Primary Hyperaldosteronism characterizes elevated plasma and urinary aldosterone with suppression of plasma renin activity. Suppression can be due to sodium retention which is aldosterone dependent and extracellular volume expansion. Here a 29 year old male presented with uncontrolled hypertension, on work up he was diagnosed to have primary Hyperaldosteronism with normal plasma renin level. So with the available medical data on the patient as well as the publications on aldosterone/renin association in primary hyperaldosteronism was reviewed here to explain the rare finding.

Key concepts: Hyperaldosteronism, Plasma renin activity, Aldosterone, Internal medicine, Renin–angiotensin system, Endocrinology, Medicine, Urinary system

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