2020•DefinitionsOpen access

Arachidonate 5-Lipoxygenase

National Cancer Institute

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Abstract

Arachidonate 5-lipoxygenase protein (674 aa, ~78 kDa) is encoded by the human ALOX5 gene. This protein plays a role in the synthesis of leukotrienes from arachidonic acid; thus, it mediates both inflammation and allergen responses.

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Arachidonate 5-lipoxygenase protein (674 aa, ~78 kDa) is encoded by the human ALOX5 gene. This protein plays a role in the synthesis of leukotrienes from arachidonic acid; thus, it mediates both inflammation and allergen responses.

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Available abstract

Arachidonate 5-lipoxygenase protein (674 aa, ~78 kDa) is encoded by the human ALOX5 gene. This protein plays a role in the synthesis of leukotrienes from arachidonic acid; thus, it mediates both inflammation and allergen responses.

Key concepts: Lipoxygenase, Arachidonate 5-lipoxygenase, Arachidonic acid, Leukotriene, Chemistry, Allergen, Inflammation, Hydroxyeicosatetraenoic acid

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