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2000•Catheterization and Cardiovascular InterventionsRequires access

Outcome of patients with acute myocardial infarction who are ineligible for primary angioplasty trials

Harold L. Dauerman, Duane S. Pinto, Kalon K.L. Ho, C. Michael Gibson, Richard E. Kuntz, David J. Cohen, Donald S. Baim, Joseph P. Carrozza

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Abstract

We determined acute outcome in 148 consecutive patients with ST segment elevation myocardial infarction undergoing angioplasty including 72 patients (48.7%) considered ineligible for primary angioplasty trials. Overall, in-hospital mortality for acute infarct angioplasty was 12%, with fivefold higher mortality in the trial-ineligible group (21% vs. 4%, P = 0.003). Thus, primary angioplasty trials continue to exclude nearly 50% of acute infarction patients and reported mortality rates of primary angioplasty trials are likely to be significantly lower than the unselected in-hospital mortality rates. Cathet. Cardiovasc. Intervent. 49:237–243, 2000. © 2000 Wiley-Liss, Inc.

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What this paper is about

We determined acute outcome in 148 consecutive patients with ST segment elevation myocardial infarction undergoing angioplasty including 72 patients (48.7%) considered ineligible for primary angioplasty trials. Overall, in-hospital mortality for acute infarct angioplasty was 12%, with fivefold higher mortality in the trial-ineligible group (21% vs. 4%, P = 0.003). Thus, primary angioplasty trials continue to exclude nearly 50% of acute infarction patients and reported mortality rates of primary angioplasty trials are likely to be significantly lower than the unselected in-hospital mortality rates. Cathet. Cardiovasc. Intervent. 49:237–243, 2000. © 2000 Wiley-Liss, Inc.

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Available abstract

We determined acute outcome in 148 consecutive patients with ST segment elevation myocardial infarction undergoing angioplasty including 72 patients (48.7%) considered ineligible for primary angioplasty trials. Overall, in-hospital mortality for acute infarct angioplasty was 12%, with fivefold higher mortality in the trial-ineligible group (21% vs. 4%, P = 0.003). Thus, primary angioplasty trials continue to exclude nearly 50% of acute infarction patients and reported mortality rates of primary angioplasty trials are likely to be significantly lower than the unselected in-hospital mortality rates. Cathet. Cardiovasc. Intervent. 49:237–243, 2000. © 2000 Wiley-Liss, Inc.

Key concepts: Medicine, Primary angioplasty, Angioplasty, Myocardial infarction, Internal medicine, Cardiology, Clinical trial, Percutaneous coronary intervention

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