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2014•Asian Journal of ChemistryOpen access

A New Phenolic Amide from Stems of Cassia fistula and Their Anti-Tobacco Mosaic Virus Activities

Guiyou Liu, Juan‐Xia Yang, Huan Wang, Jie Lou, Limei Li, Xuemei Gao, Qiufen Hu, Yanqing Ye

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Abstract

A new phenolic amide, (E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-methoxyphenyl)-2-oxoethyl]-prop-2-enamide (1) was isolated from the stems of Cassia fistula. Its structure was elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compound 1 was also evaluated for its anti-tobacco mosaic virus (anti-TMV) activity and it exhibit potential anti-TMV activity with inhibition rates of 16.2 %.

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A new phenolic amide, (E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-methoxyphenyl)-2-oxoethyl]-prop-2-enamide (1) was isolated from the stems of Cassia fistula. Its structure was elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compound 1 was also evaluated for its anti-tobacco mosaic virus (anti-TMV) activity and it exhibit potential anti-TMV activity with inhibition rates of 16.2 %.

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Available abstract

A new phenolic amide, (E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-methoxyphenyl)-2-oxoethyl]-prop-2-enamide (1) was isolated from the stems of Cassia fistula. Its structure was elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compound 1 was also evaluated for its anti-tobacco mosaic virus (anti-TMV) activity and it exhibit potential anti-TMV activity with inhibition rates of 16.2 %.

Key concepts: Tobacco mosaic virus, Cassia, Chemistry, Amide, Mosaic virus, Stereochemistry, Tobacco etch virus, Virus

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