2006•Encyclopedia of Life SciencesRequires access

Glucose‐6‐Phosphate Dehydrogenase (G6PD) Deficiency: Genetics

Philip J. Mason, Thomas J. Vulliamy

Abstract

Abstract Deficiency of glucose‐6‐phosphate dehydrogenase (G6PD) is the most common enzyme deficiency in humans and has many different local variants. The enzyme deficiency is manifested mainly in red cells, where it can lead to acute hemolytic anemia caused by failure to prevent oxidative damage. Its prevalence is due to the fact that it confers a selective advantage against malaria infection.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Glucose-6-phosphate dehydrogenase deficiency, Enzyme deficiency, Glucosephosphate Dehydrogenase Deficiency, Dehydrogenase, Malaria, Glucose-6-phosphate dehydrogenase, Hemolytic anemia, Enzyme