2021Austin Journal of Clinical PathologyRequires access

Ductal Carcinoma In situ with Focal Invasion Arising in Fibroadenoma: A Case Report and Review of Literature

Adarsh Mishra, Pooja Ramakant, C Rana, Kaushal Kishor Singh, Suresh Babu, A Singhai

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Abstract

Fibroadenoma is the most commonly diagnosed benign tumor of the breast with highest occurrence in adolescent and young women. Its coexistence with invasive ductal carcinoma is extremely rare and infrequently reported. We report a case of 30-year-old female who was diagnosed with extensive ductal carcinoma in situ with focal invasion within fibroadenoma on lumpectomy. The carcinoma was detected incidentally on histopathological examination. Therefore a careful and extensive sampling of the tissue is required to prevent a false negative diagnosis by pathologists.

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Fibroadenoma is the most commonly diagnosed benign tumor of the breast with highest occurrence in adolescent and young women. Its coexistence with invasive ductal carcinoma is extremely rare and infrequently reported. We report a case of 30-year-old female who was diagnosed with extensive ductal carcinoma in situ with focal invasion within fibroadenoma on lumpectomy. The carcinoma was detected incidentally on histopathological examination. Therefore a careful and extensive sampling of the tissue is required to prevent a false negative diagnosis by pathologists.

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Available abstract

Fibroadenoma is the most commonly diagnosed benign tumor of the breast with highest occurrence in adolescent and young women. Its coexistence with invasive ductal carcinoma is extremely rare and infrequently reported. We report a case of 30-year-old female who was diagnosed with extensive ductal carcinoma in situ with focal invasion within fibroadenoma on lumpectomy. The carcinoma was detected incidentally on histopathological examination. Therefore a careful and extensive sampling of the tissue is required to prevent a false negative diagnosis by pathologists.

Key concepts: Fibroadenoma, Lumpectomy, Ductal carcinoma, Medicine, Pathology, Carcinoma, Invasive ductal carcinoma, Histopathological examination

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