1992•Journal of the American College of ToxicologyRequires access

3 Final Report on the Safety Assessment of Isopropyl Isostearate

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Abstract

Isopropyl Isostearate, the ester of isopropyl alcohol and isostearic acid, is used as a skin conditioning agent-emollient in cosmetic products. Undiluted Isopropyl Isostearate was classified as a slight ocular irritant. Repeated applications of a 10.0% aqueous suspension of Isopropyl Isostearate to the skin of albino rabbits was well-tolerated. Based upon the safety test data on chemically similar isopropyl esters that is summarized in the report, it is concluded that Isopropyl Isostearate is safe as a cosmetic ingredient in the present practices of use and concentration.

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Key concepts: Isopropyl, Isopropyl alcohol, Isopropyl myristate, Aqueous suspension, Chemistry, Active ingredient, Medicine, Chromatography