1985•British Medical BulletinRequires access
VIRAL IMMUNOPATHOLOGY
J. G. P. Sissons, L K Borysiewiez
Open publisher page 22 citations
Abstract
The study of virus infections in experimental animals has led to the definition of the individual components of the host response, and their relative roles in the resolution of the infection. However, these immune responses can be perturbed by direct virus infection of immunocompetent cells, and effective responses may produce tissue damage for exmple by immune complex formation and T cell-mediated destruction of infected cells. This virus immunopathology assumes particular importance when the virus itself is relatively non-cytopathic and in the case of peristent infections.