1999•Journal of Chemical ResearchOpen access

Chemoselective Hydrolysis of Esters by Fungal Lipase

Abhijit Roy Chowdhury, Manish Kumar Tripathi, Umesh K. Jinwal, Uma Roy, Versha V. Kumar, A. P. BHADURI, Prasun Kumar Roy

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Abstract

Lipase, isolated from Aspergillus niger, exhibits chemoselectivity towards hydrolysis of fatty acid esters and does not hydrolyse carbamates; this has been demonstrated with substrates such as 5 ( N-methoxycarbonyl- N-ethoxycarbonylmethylamino)-2-aryl-2,4-dihydro-3 H-1,2,4-triazol-3-ones.

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Key concepts: Lipase, Chemoselectivity, Hydrolysis, Aspergillus niger, Chemistry, Organic chemistry, Fatty acid, Triacylglycerol lipase