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Periosteum Transplantation

Ronny Lorentzon, H. Alfredson

Open publisher page 9 citations

Abstract

Full thickness defects or injuries of the articular cartilage are often associated with disabling pain and impaired daily activities. These injuries may progress to secondary osteoarthrosis. It is important to treat these patients and try to accomplish regeneration of articular cartilage, especially in younger patients. Cells in the cambium layer of the periosteum are pluripotent and can differentiate into hyaline (or hyaline-like) cartilage. Autologous periosteum transplants, and autologous chon-drocytes—periosteum, have been used in the treatment of full thickness cartilage defects in the knee joint. The results vary. Postoperatively, the type of rehabilitation may be of great importance, e.g. continuous passive motion (CPM) in the immediate postoperative period.

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What this paper is about

Full thickness defects or injuries of the articular cartilage are often associated with disabling pain and impaired daily activities. These injuries may progress to secondary osteoarthrosis. It is important to treat these patients and try to accomplish regeneration of articular cartilage, especially in younger patients. Cells in the cambium layer of the periosteum are pluripotent and can differentiate into hyaline (or hyaline-like) cartilage. Autologous periosteum transplants, and autologous chon-drocytes—periosteum, have been used in the treatment of full thickness cartilage defects in the knee joint. The results vary. Postoperatively, the type of rehabilitation may be of great importance, e.g. continuous passive motion (CPM) in the immediate postoperative period.

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OpenAlex reports 9 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Full thickness defects or injuries of the articular cartilage are often associated with disabling pain and impaired daily activities. These injuries may progress to secondary osteoarthrosis. It is important to treat these patients and try to accomplish regeneration of articular cartilage, especially in younger patients. Cells in the cambium layer of the periosteum are pluripotent and can differentiate into hyaline (or hyaline-like) cartilage. Autologous periosteum transplants, and autologous chon-drocytes—periosteum, have been used in the treatment of full thickness cartilage defects in the knee joint. The results vary. Postoperatively, the type of rehabilitation may be of great importance, e.g. continuous passive motion (CPM) in the immediate postoperative period.

Key concepts: Periosteum, Medicine, Hyaline cartilage, Cartilage, Transplantation, Articular cartilage, Continuous passive motion, Surgery

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