2017Cancer DiscoveryRequires access

Brentuximab Beats Standard Therapies for CTCL

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Abstract

Compared with a physician's choice of either methotrexate or bexarotene, the CD30-directed antibody-drug conjugate brentuximab vedotin led to significantly superior clinical responses in patients with cutaneous T-cell lymphomas, according to the results of the international phase III ALCANZA trial.

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What this paper is about

Compared with a physician's choice of either methotrexate or bexarotene, the CD30-directed antibody-drug conjugate brentuximab vedotin led to significantly superior clinical responses in patients with cutaneous T-cell lymphomas, according to the results of the international phase III ALCANZA trial.

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Available abstract

Compared with a physician's choice of either methotrexate or bexarotene, the CD30-directed antibody-drug conjugate brentuximab vedotin led to significantly superior clinical responses in patients with cutaneous T-cell lymphomas, according to the results of the international phase III ALCANZA trial.

Key concepts: Brentuximab vedotin, Bexarotene, Methotrexate, Antibody-drug conjugate, Medicine, Internal medicine, Oncology, Clinical trial

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