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1963•Clinical Pharmacology & TherapeuticsRequires access

A comparison of the value of 200,000 I.U. tetanus antitoxin with 50,000 I.U. in the treatment of tetanus

B. J. Vakil, T. H. Tulpule, P. Armitage, D. R. Laurence

Open publisher page 9 citations

Abstract

In view of the lack of adequate data on the proper dosage of antitoxin in clinical tetanus, a comparison of two doses was undertaken. Patients were allotted at random after diagnosis to receive 200,000 I.U. or 50,000 I.U. antitoxin. Altogether 293 cases were included. Analysis of the results indicates that the lower dose is as effective as the higher.

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What this paper is about

In view of the lack of adequate data on the proper dosage of antitoxin in clinical tetanus, a comparison of two doses was undertaken. Patients were allotted at random after diagnosis to receive 200,000 I.U. or 50,000 I.U. antitoxin. Altogether 293 cases were included. Analysis of the results indicates that the lower dose is as effective as the higher.

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OpenAlex reports 9 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

In view of the lack of adequate data on the proper dosage of antitoxin in clinical tetanus, a comparison of two doses was undertaken. Patients were allotted at random after diagnosis to receive 200,000 I.U. or 50,000 I.U. antitoxin. Altogether 293 cases were included. Analysis of the results indicates that the lower dose is as effective as the higher.

Key concepts: Antitoxin, Tetanus antitoxin, Tetanus, Medicine, Value (mathematics), Pediatrics, Statistics, Immunology

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