[Male sterility and reciprocal translocation (4;15). Description of a case].
Giovanna Piovani, Paola Zanelli, Tui Néri, Monia Savi
Abstract
Giovanna Piovani, Paola Zanelli, Tui Néri, Monia Savi
Abstract
Chromosome abnormalities in infertile males are not infrequent, ranging from 4% to about 1% for sex and autosomal chromosomes respectively. Autosomal abnormalities mainly consist of balanced translocations, mostly robertsonian. The Authors report a case of reciprocal translocation t (4;15) associated with oligozoospermia and sterility in a 37 years-old man. The break-points involved in the translocation (4q25; 15p11) seem to be quite uncommon. The possible relationship between this unusual translocation and sterility is discussed.
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Chromosome abnormalities in infertile males are not infrequent, ranging from 4% to about 1% for sex and autosomal chromosomes respectively. Autosomal abnormalities mainly consist of balanced translocations, mostly robertsonian. The Authors report a case of reciprocal translocation t (4;15) associated with oligozoospermia and sterility in a 37 years-old man. The break-points involved in the translocation (4q25; 15p11) seem to be quite uncommon. The possible relationship between this unusual translocation and sterility is discussed.
Key concepts: Chromosomal translocation, Sterility, Genetics, Biology, Chromosome, Robertsonian translocation, Reciprocal, Karyotype