Morphological alterations of Pseudomonas aeruginosa and Escherichia coli by nocardicin A

Pseudomonas aeruginosa and Escherichia coli were exposed to nocardicin A, and were subsequently observed with transmission and scanning electron microscopes. Although the nocardicin A-induced morphological alterations such as bulges and spheroplast formations were observed both in P. aeruginosa and E. coli, their positions on the cell surface were different in the two species.