2007•Faculty Opinions – Post-Publication Peer Review of the Biomedical LiteratureRequires access
Faculty Opinions recommendation of Alternative donor substrates for inverting and retaining glycosyltransferases.
Nicola L. B. Pohl
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Abstract
By the use of glycosyl donors containing aromatic leaving groups linked with opposite anomeric configurations compared to those of the natural donor substrates, an inverting (Cst II) and a retaining (LgtC) glycosyltransferase were found to catalyse glycosylation reactions of natural acceptor substrates in the presence of the corresponding nucleotide. PMID: 17220972