1997•Biomedical ChromatographyRequires access

Direct HPLC separation of β-aminoester enantiomers on totally synthetic chiral stationary phases

F. Gasparrini, I. D'Acquarica, Claudio Villani, C Cimarelli, G. Palmieri

Abstract

The direct separation of β-aminoester enantiomers by HPLC on synthetic chiral stationary phases based on a π-acidic derivative of trans 1,2-diaminocyclohexane as selector is described. The application of different columns containing the stationary phase with opposite configurations and in the racemic form to the determination of enantiomeric excess in chemically impure samples is demonstrated. © 1997 John Wiley & Sons, Ltd.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Enantiomer, Chemistry, Chiral stationary phase, Chromatography, Stationary phase, High-performance liquid chromatography, Derivative (finance), Chromatographic separation