A Novel Reductive Amino Cyclization Method and Its Application for the Syntheses of Pyrrolidine and Piperidine Nucleus
Masanori Somei, Fumio Yamada, Toshifumi Hasegawa, Masayuki Wakita, Mitsuru Sugiyama
Abstract
Masanori Somei, Fumio Yamada, Toshifumi Hasegawa, Masayuki Wakita, Mitsuru Sugiyama
Abstract
A novel synthetic method for pyrrolidine and piperidine derivatives is developed.Its versatility is proved by the syntheses of 6a,9a-e-6,6a,7,8,9,9a-hexahydro-25-iso- indolol4,5,6-cdlindole and cactus alkaloid, (?)-lophocerine.
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A novel synthetic method for pyrrolidine and piperidine derivatives is developed.Its versatility is proved by the syntheses of 6a,9a-e-6,6a,7,8,9,9a-hexahydro-25-iso- indolol4,5,6-cdlindole and cactus alkaloid, (?)-lophocerine.
Key concepts: Pyrrolidine, Piperidine, Chemistry, Alkaloid, Stereochemistry, Organic chemistry, Combinatorial chemistry