Senna

This chapter presents indications, clinical evidence, pre-clinical evidence, mechanisms of action, interactions, and contraindications of Senna (Senna alexandrina Mill.). Senna products are used for the short-term relief of occasional constipation and are available both on prescription and over-the-counter. Dried senna pods, and the leaves, often as tea bags, are sometimes used to make an infusion (tea). Adverse effects, dosage, and general plant information are included in the chapter. S. alexandrina has a long tradition of use and has been an important item of trade, especially in Arabic medicine. Senna is now a pan-tropical species but mostly grown in Southern India for commerce.