Juvenile Idiopathic Arthritis associated Uveitis: Diagnosis, Clinic, and Treatment
Sibel Kadayıfçılar
Abstract
Sibel Kadayıfçılar
Abstract
Uveitis is the most common extraarticular finding in juvenile idiopathic arthritis (JIA). Non-granulomatous, chronic, insidious onset of anterior uveitis does not show any symptoms, so complications are often seen at the time of diagnosis. Therefore, periodic screening is necessary in JIA cases. Topical corticosteroid therapy is the first approach when diagnosed early and immunosuppressive therapy is necessary if remission cannot be achieved or if there is an initial complication. For this purpose, the first choice is methotrexate and the second step is biological agents such as adalimumab or infliximab. Surgical treatment is required for complications such as cataract and glaucoma.
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Uveitis is the most common extraarticular finding in juvenile idiopathic arthritis (JIA). Non-granulomatous, chronic, insidious onset of anterior uveitis does not show any symptoms, so complications are often seen at the time of diagnosis. Therefore, periodic screening is necessary in JIA cases. Topical corticosteroid therapy is the first approach when diagnosed early and immunosuppressive therapy is necessary if remission cannot be achieved or if there is an initial complication. For this purpose, the first choice is methotrexate and the second step is biological agents such as adalimumab or infliximab. Surgical treatment is required for complications such as cataract and glaucoma.
Key concepts: Medicine, Uveitis, Adalimumab, Infliximab, Anterior uveitis, Arthritis, Methotrexate, Complication