1957New England Journal of MedicineRequires access

Antibiotic Combinations

Wilfred F. Jones, Maxwell Finland, Clare Wilcox, Ann Najarian, Mildred W. Barnes

Open publisher page 5 citations

Abstract

Antibacterial Action of Plasma after Ingestion of Tetracycline, Erythromycin, Oleandomycin, Spiramycin and Combinations of Tetracycline and Each of the Other 3 AntibioticsThe activity of the antibiotics under study was compared in vivo in two ways: as single doses of 1.0 gm. of each of the 4 individual agents and equal total amounts (0.5 gm. each) of tetracycline in pairs with each of the other 3 drugs; and as a single dose of 500 mg. of tetracycline alone compared with the same amount of this antibiotic combined with 250 mg. of either erythromycin, oleandomycin or spiramycin. The doses were all . . .

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Antibacterial Action of Plasma after Ingestion of Tetracycline, Erythromycin, Oleandomycin, Spiramycin and Combinations of Tetracycline and Each of the Other 3 AntibioticsThe activity of the antibiotics under study was compared in vivo in two ways: as single doses of 1.0 gm. of each of the 4 individual agents and equal total amounts (0.5 gm. each) of tetracycline in pairs with each of the other 3 drugs; and as a single dose of 500 mg. of tetracycline alone compared with the same amount of this antibiotic combined with 250 mg. of either erythromycin, oleandomycin or spiramycin. The doses were all . . .

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Available abstract

Antibacterial Action of Plasma after Ingestion of Tetracycline, Erythromycin, Oleandomycin, Spiramycin and Combinations of Tetracycline and Each of the Other 3 AntibioticsThe activity of the antibiotics under study was compared in vivo in two ways: as single doses of 1.0 gm. of each of the 4 individual agents and equal total amounts (0.5 gm. each) of tetracycline in pairs with each of the other 3 drugs; and as a single dose of 500 mg. of tetracycline alone compared with the same amount of this antibiotic combined with 250 mg. of either erythromycin, oleandomycin or spiramycin. The doses were all . . .

Key concepts: Oleandomycin, Spiramycin, Tetracycline, Erythromycin, Antibiotics, Medicine, Microbiology, Pharmacology

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