2021Journal of Forensic Medicine and ToxicologyRequires access

Autopsy study of sudden cardiac death

Sharnagat Nitin, Ambade Vipul, Gilbe Pratik, Sharma Manu, Bhagwat Deepak

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Abstract

BackgroundThe causes of sudden cardiac death are undetected despite detailed postmortem examination, histological examination and toxicological analysis leading to negative autopsy in some cases. The present study is carried out with a view to evaluate the victims of sudden cardiac death (SCD) brought for medicolegal autopsy.The present cross sectional study included 74 cases of sudden cardiac death within 24 hours with history of chest pain or known ischaemic heart disease brought for medicolegal autopsy. During the autopsy, heart and coronaries were dissected to find out any pathology and the subjected for histopathological examination.ResultsThe victims of SCD were mostly males (85.1%) with peak incidence in older ages above 60years (41.9%). Almost 84% of the victims had survival period of less than 6 hours. Left anterior descending artery (64.9%) was the commonest coronary artery involved with atherosclerosis. Most of the victims had double vessel block with 71.6% had coronary narrowing exceeding 75% stenosis. There was statistically significant positive correlation between the coronary block and the age of the victim of sudden cardiac death (p=0.007).Careful and detailed autopsy can be conducted in SCD to find out its cause.

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BackgroundThe causes of sudden cardiac death are undetected despite detailed postmortem examination, histological examination and toxicological analysis leading to negative autopsy in some cases. The present study is carried out with a view to evaluate the victims of sudden cardiac death (SCD) brought for medicolegal autopsy.The present cross sectional study included 74 cases of sudden cardiac death within 24 hours with history of chest pain or known ischaemic heart disease brought for medicolegal autopsy. During the autopsy, heart and coronaries were dissected to find out any pathology and the subjected for histopathological examination.ResultsThe victims of SCD were mostly males (85.1%) with peak incidence in older ages above 60years (41.9%). Almost 84% of the victims had survival period of less than 6 hours. Left anterior descending artery (64.9%) was the commonest coronary artery involved with atherosclerosis. Most of the victims had double vessel block with 71.6% had coronary narrowing exceeding 75% stenosis. There was statistically significant positive correlation between the coronary block and the age of the victim of sudden cardiac death (p=0.007).Careful and detailed autopsy can be conducted in SCD to find out its cause.

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Available abstract

BackgroundThe causes of sudden cardiac death are undetected despite detailed postmortem examination, histological examination and toxicological analysis leading to negative autopsy in some cases. The present study is carried out with a view to evaluate the victims of sudden cardiac death (SCD) brought for medicolegal autopsy.The present cross sectional study included 74 cases of sudden cardiac death within 24 hours with history of chest pain or known ischaemic heart disease brought for medicolegal autopsy. During the autopsy, heart and coronaries were dissected to find out any pathology and the subjected for histopathological examination.ResultsThe victims of SCD were mostly males (85.1%) with peak incidence in older ages above 60years (41.9%). Almost 84% of the victims had survival period of less than 6 hours. Left anterior descending artery (64.9%) was the commonest coronary artery involved with atherosclerosis. Most of the victims had double vessel block with 71.6% had coronary narrowing exceeding 75% stenosis. There was statistically significant positive correlation between the coronary block and the age of the victim of sudden cardiac death (p=0.007).Careful and detailed autopsy can be conducted in SCD to find out its cause.

Key concepts: Autopsy, Sudden cardiac death, Cardiology, Medicine, Internal medicine

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