Anti-epiligrin (laminin 5) cicatricial pemphigoid
Jill I. Allbritton, Hossein C. Nousari, Grant J. Anhalt
Abstract
Jill I. Allbritton, Hossein C. Nousari, Grant J. Anhalt
Abstract
Cicatricial pemphigoid is an autoimmune disease predominantly of elderly patients. Recently, a subtype of cicatricial pemphigoid with antibodies to epiligrin (laminin 5) was described. We report a patient in whom anti‐epiligrin cicatricial pemphigoid was identified. He presented with cutaneous, oral and ocular involvement. He has shown initial improvement on corticosteroids and cyclophosphamide.
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Cicatricial pemphigoid is an autoimmune disease predominantly of elderly patients. Recently, a subtype of cicatricial pemphigoid with antibodies to epiligrin (laminin 5) was described. We report a patient in whom anti‐epiligrin cicatricial pemphigoid was identified. He presented with cutaneous, oral and ocular involvement. He has shown initial improvement on corticosteroids and cyclophosphamide.
Key concepts: Cicatricial pemphigoid, Medicine, Pemphigoid, Dermatology, Cyclophosphamide, Autoimmune disease, Laminin, Antibody