ScholarLens Back to search
2010•Comprehensive Organic Name Reactions and ReagentsRequires access

Trost Desymmetrization

Author information unavailable

Open publisher page 0 citations

Abstract

Abstract Desymmetrization means to remove a symmetric element from the substrate and it may take place in the presence of an enzyme or a nonenzymatic catalyst. Among the known nonenzymatic desymmetrization processes, the most common one is the palladium‐catalyzed desymmetrization of meso ‐2‐ene‐1,4‐diols. Overall, the desymmetrization of meso ‐compounds is getting popular because it can offer asymmetric synthons of high value via a limited number of steps. Many desymmtrization protocols have been summarized. This type of transformation has wide application in organic synthesis.

About this research paper

What this paper is about

Abstract Desymmetrization means to remove a symmetric element from the substrate and it may take place in the presence of an enzyme or a nonenzymatic catalyst. Among the known nonenzymatic desymmetrization processes, the most common one is the palladium‐catalyzed desymmetrization of meso ‐2‐ene‐1,4‐diols. Overall, the desymmetrization of meso ‐compounds is getting popular because it can offer asymmetric synthons of high value via a limited number of steps. Many desymmtrization protocols have been summarized. This type of transformation has wide application in organic synthesis.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Abstract Desymmetrization means to remove a symmetric element from the substrate and it may take place in the presence of an enzyme or a nonenzymatic catalyst. Among the known nonenzymatic desymmetrization processes, the most common one is the palladium‐catalyzed desymmetrization of meso ‐2‐ene‐1,4‐diols. Overall, the desymmetrization of meso ‐compounds is getting popular because it can offer asymmetric synthons of high value via a limited number of steps. Many desymmtrization protocols have been summarized. This type of transformation has wide application in organic synthesis.

Key concepts: Desymmetrization, Synthon, Chemistry, Catalysis, Substrate (aquarium), Palladium, Transformation (genetics), Organic chemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Trost Desymmetrization — Research Paper | ScholarLens