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2020•Unpublished venueOpen access

Antenatal Administration of Betamethasone Contributes to Intimal Thickening of the Ductus Arteriosus

Takahiro Kemmotsu, Utako Yokoyama, Junichi Saito, Satoko Ito, Azusa Uozumi, Shiho Iwasaki, Shigeru Nishimaki, Shuichi Ito, Munetaka Masuda, Toshihide Asou, Yoshihiro Ishikawa

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Abstract

Abstract Antenatal betamethasone (BTM) is a standard therapy to reduce respiratory distress syndrome [1], and some reports indicate that BTM decreases prevalence of patent ductus arteriosus in preterm infants [2]. Closure of the ductus arteriosus (DA) requires morphological remodeling, i.e., intimal thickening (IT) formation [3]. However, the role of BTM in IT formation of the preterm DA has not been reported.

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What this paper is about

Abstract Antenatal betamethasone (BTM) is a standard therapy to reduce respiratory distress syndrome [1], and some reports indicate that BTM decreases prevalence of patent ductus arteriosus in preterm infants [2]. Closure of the ductus arteriosus (DA) requires morphological remodeling, i.e., intimal thickening (IT) formation [3]. However, the role of BTM in IT formation of the preterm DA has not been reported.

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Available abstract

Abstract Antenatal betamethasone (BTM) is a standard therapy to reduce respiratory distress syndrome [1], and some reports indicate that BTM decreases prevalence of patent ductus arteriosus in preterm infants [2]. Closure of the ductus arteriosus (DA) requires morphological remodeling, i.e., intimal thickening (IT) formation [3]. However, the role of BTM in IT formation of the preterm DA has not been reported.

Key concepts: Ductus arteriosus, Betamethasone, Thickening, Medicine, Respiratory distress, Cardiology, Internal medicine, Anesthesia

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