A Comparison between Intrathecal Bupivacaine alone and Intrathecal Bupivacaine in Combination with Nalbuphine for Post-Operative Analgesia

Background: In this study, we compared intrathecal Bupivacaine alone and intrathecal Bupivacaine in combination withNalbuphine in terms of post-operative analgesia.Methods: 50 patients of ASA physical status I & II, aged 16-55 years, of either gender, undergoing elective lower abdominal and lower limb orthopaedic surgeries under subarachnoid block were enrolled in this study.Patients were divided into 2 groups of 25 each.Assessment of motor and sensory blockade was done by Bromage scale and pin-prick method.Post-operative analgesia was assessed by VAS score.Results: There is no significant difference between the 2 groups for onset of motor and sensory blockade.Two segment regression time of sensory blockade and duration of effective analgesia were prolonged in the Nalbuphine group.Conclusion: In this study we found that intrathecal Nalbuphine in the dose of 0.8mg along with Bupivacaine produces prolonged post-operative analgesia without increased incidence of side effects.