A method of intra-ventricular bioimpedance spectroscopy to estimate the dynamic volume of right ventricle

Dynamic volume measurements of the heart are primarily done in the left ventricle, but as the right ventricle is a frequent place for pacing electrodes it could be easier to estimate cardiac output through the right ventricle. Our goal was to find the correlation between intra-cardiac bioimpedance deviations and the variations related to changes of the right ventricle volume. The variations of right ventricle volume have been evaluated experimentally using a setup with an isolated pig heart. Measurements were made with an intra-ventricular catheter and using multifrequency impedance spectroscopy.