1998Chemical and Pharmaceutical BulletinOpen access

Studies on the Constituents of Epimedium koreanum. III.

Pengyue SUN, Yingjie CHEN, Noriko Shimizu, Tadahiro Takeda

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Abstract

A new flavonol glycoside, epimedin I (1), a new chromone, 5, 7-dihydroxy-2-(p-hydroxy-phenoxy)-6-prenyl-chromone (2), and icariside A7 (3) were isolated from the aerial parts of Epimedium koreanum NAKAI (Berberidaceae) together with six known compounds, chaohuoside A (epimedin L) (4), 8-prenylkaempferol (5), anhydroicaritin (6), ginkgetin (7), isoginkgetin (8) and bilobetin (9). Their structures were established by spectroscopic methods and chemical evidence.

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A new flavonol glycoside, epimedin I (1), a new chromone, 5, 7-dihydroxy-2-(p-hydroxy-phenoxy)-6-prenyl-chromone (2), and icariside A7 (3) were isolated from the aerial parts of Epimedium koreanum NAKAI (Berberidaceae) together with six known compounds, chaohuoside A (epimedin L) (4), 8-prenylkaempferol (5), anhydroicaritin (6), ginkgetin (7), isoginkgetin (8) and bilobetin (9). Their structures were established by spectroscopic methods and chemical evidence.

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Available abstract

A new flavonol glycoside, epimedin I (1), a new chromone, 5, 7-dihydroxy-2-(p-hydroxy-phenoxy)-6-prenyl-chromone (2), and icariside A7 (3) were isolated from the aerial parts of Epimedium koreanum NAKAI (Berberidaceae) together with six known compounds, chaohuoside A (epimedin L) (4), 8-prenylkaempferol (5), anhydroicaritin (6), ginkgetin (7), isoginkgetin (8) and bilobetin (9). Their structures were established by spectroscopic methods and chemical evidence.

Key concepts: Icariin, Berberidaceae, Chromone, Chemistry, Epimedium, Glycoside, Prenylation, Stereochemistry

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