1996•Journal of the European Academy of Dermatology and VenereologyRequires access

Hypereosinophilic syndrome as prodrome of bullous pemphigoid: report of a case

Giovanni Maria Palleschi

Abstract

Persistent hypereosinophilia, cardiac involvement and a recurrent erythematous-papular pruritic eruption histologically characterized by eosinophilic spongiosis are described in a 77-year-old man. This condition, suggestive of “idiopathic” hypereosinophilic syndrome, represented the prodromic phase of atypical bullous pemphigoid, which manifested 7 months later.

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Key concepts: Medicine, Hypereosinophilia, Prodrome, Bullous pemphigoid, Hypereosinophilic syndrome, Dermatology, Spongiosis, Eosinophilia