2021•Cambridge University Press eBooksRequires access
Adrenoceptor Antagonists
Tom E. Peck, Benjamin T. Harris
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Abstract
α-Adrenoceptor antagonists (α-blockers) prevent the actions of sympathomimetic agents on α-adrenoceptors. Certain α-blockers (phentolamine, phenoxybenzamine) are non-specific and inhibit both α 1 - and α 2 -receptors, whereas others selectively inhibit α 1 -receptors (prazosin) or α 2 -receptors (yohimbine). The actions of specific α-adrenoceptor stimulation are shown in Table 14.1.