Functional tremor developing after successful MRI-guided focused ultrasound thalamotomy for essential tremor
Sohaila Alshimemeri, Daniel Vargas-Méndez, Robert Chen, Nir Lipsman, Michael L. Schwartz, Andrés M. Lozano, Alfonso Fasano
Abstract
Sohaila Alshimemeri, Daniel Vargas-Méndez, Robert Chen, Nir Lipsman, Michael L. Schwartz, Andrés M. Lozano, Alfonso Fasano
Abstract
OBJECTIVE: To describe a case of functional tremor occurring after a successful MR-guided focused ultrasound thalamotomy (MRgFUS) for essential tremor. METHODS: A 71-year-old right-handed man with essential tremor was referred to us for consideration of deep brain stimulation surgery for worsening bilateral upper limb tremor after a successful left MRgFUS for essential tremor. RESULTS: On clinical exam, signs compatible with a functional tremor were noted, including entertainability and suppressibility. Electrophysiological studies were consistent with essential tremor and superimposed tremor fulfilling the laboratory-supported criteria for functional tremor. DISCUSSION: We describe the first reported case of a functional movement disorder occurring after successful MRgFUS procedure for essential tremor. Recognising this entity and its development after such therapeutic interventions is essential to avoid further unnecessary invasive therapies.
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OBJECTIVE: To describe a case of functional tremor occurring after a successful MR-guided focused ultrasound thalamotomy (MRgFUS) for essential tremor. METHODS: A 71-year-old right-handed man with essential tremor was referred to us for consideration of deep brain stimulation surgery for worsening bilateral upper limb tremor after a successful left MRgFUS for essential tremor. RESULTS: On clinical exam, signs compatible with a functional tremor were noted, including entertainability and suppressibility. Electrophysiological studies were consistent with essential tremor and superimposed tremor fulfilling the laboratory-supported criteria for functional tremor. DISCUSSION: We describe the first reported case of a functional movement disorder occurring after successful MRgFUS procedure for essential tremor. Recognising this entity and its development after such therapeutic interventions is essential to avoid further unnecessary invasive therapies.
Key concepts: Essential tremor, Thalamotomy, Medicine, Movement disorders, Physical medicine and rehabilitation, Deep brain stimulation, Thalamic stimulator, Neuroscience