Commentary on: Efficacy of Tranexamic Acid in Reducing Seroma and Hematoma Formation Following Reduction Mammaplasty

See the Original Article here. It was a pleasure to review the article “Efficacy of Tranexamic Acid (TXA) in Reducing Seroma and Hematoma Formation Following Reduction Mammaplasty.” 1 The study is a retrospective review of 385 consecutive patients who experienced bilateral reduction mammaplasty. Topical TXA was utilized in 66.8% of the cases, and intravenous TXA was utilized in 33.1% of the cases. The authors should be commended for publishing the largest study on the utilization of intravenous and topical TXA. They concluded the utilization of drains significantly reduced the risk of seroma and stated there was no reduction in risk when utilizing TXA in breast reduction surgery. Essentially, the authors concluded that there was no benefit of utilizing either intravenous or topical TXA. This finding is quite interesting considering other articles have revealed a trend towards decrease in drainage output. Ausin et al found median fluid output decreased 42%...