2022•HaematologicaOpen access

The first achievement of complete remission in childhood leukemia by treatment with the folic acid antagonist aminopterin

Shai Izraeli

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Abstract

TITLE Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid (aminopterin). AUTHORS Farber S, Diamond LK. Mercer RD, Slyvester RF Jr, Wolff JA. JOURNAL New England Journal of Medicine. 1948;238(23):787-793. https://pubmed.ncbi.nlm.nih.gov/18860765/

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TITLE Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid (aminopterin). AUTHORS Farber S, Diamond LK. Mercer RD, Slyvester RF Jr, Wolff JA. JOURNAL New England Journal of Medicine. 1948;238(23):787-793. https://pubmed.ncbi.nlm.nih.gov/18860765/

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TITLE Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid (aminopterin). AUTHORS Farber S, Diamond LK. Mercer RD, Slyvester RF Jr, Wolff JA. JOURNAL New England Journal of Medicine. 1948;238(23):787-793. https://pubmed.ncbi.nlm.nih.gov/18860765/

Key concepts: Aminopterin, Folic Acid Antagonists, Folic acid, Medicine, Leukemia, Antagonist, Pediatrics, Internal medicine

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