2022•Nature MicrobiologyOpen access

Spacer prioritization in CRISPR–Cas9 immunity is enabled by the leader RNA

Chunyu Liao, Sahil Sharma, Sarah L. Svensson, Anuja Kibe, Zasha Weinberg, Omer S. Alkhnbashi, Thorsten Bischler, Rolf Backofen, Neva Caliskan, Cynthia M. Sharma, Chase L. Beisel

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Key concepts: Trans-activating crRNA, CRISPR, Cas9, Biology, RNA, Computational biology, CRISPR interference, Plasmid

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Spacer prioritization in CRISPR–Cas9 immunity is enabled by the leader RNA — Research Paper | ScholarLens