Tissue thromboplastin
R. F. Baikeev
Abstract
Open-access reader
R. F. Baikeev
Abstract
Open-access reader
The appearance of tissue thromboplastin (factor III, tissue factor) in the bloodstream leads to one of the most dangerous non-specific disorders of hemocoagulation - disseminated intravascular clotting (DIC). Although the components of the thromboplastin reaction are known, the molecular organization of tissue thromboplastin to the extent necessary to understand the initiation of the external pathway of the blood coagulation system has not been detailed to date.
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The appearance of tissue thromboplastin (factor III, tissue factor) in the bloodstream leads to one of the most dangerous non-specific disorders of hemocoagulation - disseminated intravascular clotting (DIC). Although the components of the thromboplastin reaction are known, the molecular organization of tissue thromboplastin to the extent necessary to understand the initiation of the external pathway of the blood coagulation system has not been detailed to date.
Key concepts: Thromboplastin, Tissue factor, Coagulation, Disseminated intravascular coagulation, Medicine, Clotting factor, Blood clotting, Internal medicine