2022•Kidney International ReportsOpen access

POS-501 COMPLEMENT LEVELS IN ANCA ASSOCIATED VASCULITIS AS PREDECTOR OF RENAL SURVIVAL

Mariem Ben salem, Abir Gana, Ichrak Bannour, Sarah Ben Khalifa, Insaf Handous, M. Ben Salah, Mouna Hamouda, Ahmed Letaief, Sabra Aloui, H. Aounallah Skhiri

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Abstract

During the last few years, novel findings have suggested that activation of the complement system, in particular the alternative complement system, has a significant role in ANCA associated vasculitis pathogenesis. We investigated whether low serum C3 levels can cross sectionally estimate severe antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and estimate the renal servival.

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What this paper is about

During the last few years, novel findings have suggested that activation of the complement system, in particular the alternative complement system, has a significant role in ANCA associated vasculitis pathogenesis. We investigated whether low serum C3 levels can cross sectionally estimate severe antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and estimate the renal servival.

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Available abstract

During the last few years, novel findings have suggested that activation of the complement system, in particular the alternative complement system, has a significant role in ANCA associated vasculitis pathogenesis. We investigated whether low serum C3 levels can cross sectionally estimate severe antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and estimate the renal servival.

Key concepts: Medicine, Vasculitis, Anti-neutrophil cytoplasmic antibody, Complement system, Complement (music), ANCA-Associated Vasculitis, Pathogenesis, Immunology

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