2011•Methods and principles in medicinal chemistryRequires access

Cyclophilin Inhibitors

Grégoire Vuagniaux, Arnaud Hamel, Rafael Crabbé, Hervé Porchet, Jean‐Maurice Dumont

Abstract

This chapter contains sections titled: Introduction Cyclophilin Overview Cyclophilin Inhibitors Currently in Clinical Development Cyclophilin and HIV Cyclophilin and Hepatitis C Clinical Results in HCV Activity against Other Viruses New Noncyclosporine Cyclophilin Inhibitors Conclusion References

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Available abstract

Key concepts: Cyclophilin, Cyclophilin A, Peptidylprolyl isomerase, Cis-trans-Isomerases, Biology, Virology, Chemistry, Biochemistry