Function of the Retinoblastoma‐Related Protein in Plants
Wilhelm Gruissem
Abstract
Wilhelm Gruissem
Abstract
Abstract The sections in this article are Introduction Retinoblastoma Proteins and the Tumor Suppressor Concept The Retinoblastoma Pathway is Conserved in Animals and Plants Retinoblastoma Proteins form Complexes with E2F Transcription Factors to Control Entry into the Cell Cycle G1 Restriction Point Control is Mediated by Retinoblastoma Protein Phosphorylation Animal and Plant DNA Viruses Target Retinoblastoma Proteins to Induce Host DNA Replication Information on Retinoblastoma Protein Function in Animal Development is Still Incomplete Retinoblastoma Proteins may have Conserved Functions in Germline Development Retinoblastoma Proteins Connect Stem Cell Maintenance to Cell Proliferation and Differentiation Perturbation of RBR during Leaf Development Affects Cell Proliferation and Control of DNA Replication Roles of Retinoblastoma Proteins in Transcription Activation and Repression Retinoblastoma Proteins Interact with Polycomb Group Complexes in Controlling Gene Expression Conclusion Acknowledgments
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Abstract The sections in this article are Introduction Retinoblastoma Proteins and the Tumor Suppressor Concept The Retinoblastoma Pathway is Conserved in Animals and Plants Retinoblastoma Proteins form Complexes with E2F Transcription Factors to Control Entry into the Cell Cycle G1 Restriction Point Control is Mediated by Retinoblastoma Protein Phosphorylation Animal and Plant DNA Viruses Target Retinoblastoma Proteins to Induce Host DNA Replication Information on Retinoblastoma Protein Function in Animal Development is Still Incomplete Retinoblastoma Proteins may have Conserved Functions in Germline Development Retinoblastoma Proteins Connect Stem Cell Maintenance to Cell Proliferation and Differentiation Perturbation of RBR during Leaf Development Affects Cell Proliferation and Control of DNA Replication Roles of Retinoblastoma Proteins in Transcription Activation and Repression Retinoblastoma Proteins Interact with Polycomb Group Complexes in Controlling Gene Expression Conclusion Acknowledgments
Key concepts: Retinoblastoma, Retinoblastoma protein, Biology, E2F1, DNA-binding protein, E2F, Transcription factor, Gene