2022•Journal of NeurophysiologyOpen access

Dissociation between abnormal motor synergies and impaired reaching dexterity after stroke

Alkis M. Hadjiosif, Meret Branscheidt, Manuel Alejandro Anaya, Keith D. Runnalls, Jennifer L. Keller, Amy J. Bastian, Pablo A. Celnik, John W. Krakauer

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Abstract

Motor impairment is common after stroke and comprises reduced dexterity, weakness, and abnormal muscle synergies. Here we report that, when matched on an established synergy and weakness scale (Fugl-Meyer), patients with subacute stroke have worse reaching dexterity than chronic ones. This result suggests that the components of hemiparesis are dissociable and have separable mechanisms and, thus, may require distinct assessments and treatments.

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What this paper is about

Motor impairment is common after stroke and comprises reduced dexterity, weakness, and abnormal muscle synergies. Here we report that, when matched on an established synergy and weakness scale (Fugl-Meyer), patients with subacute stroke have worse reaching dexterity than chronic ones. This result suggests that the components of hemiparesis are dissociable and have separable mechanisms and, thus, may require distinct assessments and treatments.

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Available abstract

Motor impairment is common after stroke and comprises reduced dexterity, weakness, and abnormal muscle synergies. Here we report that, when matched on an established synergy and weakness scale (Fugl-Meyer), patients with subacute stroke have worse reaching dexterity than chronic ones. This result suggests that the components of hemiparesis are dissociable and have separable mechanisms and, thus, may require distinct assessments and treatments.

Key concepts: Physical medicine and rehabilitation, Neuroscience, Psychology, Dissociation (chemistry), Stroke (engine), Communication, Audiology, Medicine

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