2021Thesis Commons (OSF Preprints)Open access

Do Chloroquine and Hydroxychloroquine Treat COVID-19?

Sanaa Bouchnafati, Bouhmou Ayoub, Reda Bzikha, Bzikha Ilham

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Abstract

Chloroquine is an anti-malarial and autoimmune disease drug, which has an anti- viral activity. In vitro, the Chloroquine and Hydroxychloroquine are potent at inhibiting SARS-CoV. Therefore, Chloroquine and Hydroxychloroquine are being studied for their potential treatment of coronavirus disease 2019. Those drugs are now recommended by the FDA, and multiple health organizations. This aims of this review is to explore the efficacy of the chloroquine and hydrochloroquine in the treatment of the novel COVID-19.

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What this paper is about

Chloroquine is an anti-malarial and autoimmune disease drug, which has an anti- viral activity. In vitro, the Chloroquine and Hydroxychloroquine are potent at inhibiting SARS-CoV. Therefore, Chloroquine and Hydroxychloroquine are being studied for their potential treatment of coronavirus disease 2019. Those drugs are now recommended by the FDA, and multiple health organizations. This aims of this review is to explore the efficacy of the chloroquine and hydrochloroquine in the treatment of the novel COVID-19.

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Available abstract

Chloroquine is an anti-malarial and autoimmune disease drug, which has an anti- viral activity. In vitro, the Chloroquine and Hydroxychloroquine are potent at inhibiting SARS-CoV. Therefore, Chloroquine and Hydroxychloroquine are being studied for their potential treatment of coronavirus disease 2019. Those drugs are now recommended by the FDA, and multiple health organizations. This aims of this review is to explore the efficacy of the chloroquine and hydrochloroquine in the treatment of the novel COVID-19.

Key concepts: Hydroxychloroquine, Chloroquine, Coronavirus disease 2019 (COVID-19), Medicine, Drug, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Pharmacology, Virology

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