[Role of Contrast-enhanced Ultrasound in Distinguishing between Benign and Malignant Thyroid Nodules with Calcification].

=0.727). Conclusions The combination with contrast-enhanced ultrasound can improve the performance of conventional ultrasound in the differential diagnosis of benign and malignant thyroid solid nodules with calcification.Eight malignant signs include solid,hypoechoic,microcalcification,aspect ratio,and blurred edges detected by conventional ultrasound,and non-circular enhancement around nodules,low enhancement and non-uniform enhancement of solid parts detected by contrast-enhanced ultrasound.A solid thyroid nodule with calcification presenting five or more malignant signs highly suggests malignancy.